Patterns of c-reactive protein predicts response to therapy in healthcare-associated pneumonia in critically ill patients with cancer
نویسندگان
چکیده
Methods This was a secondary analysis of a prospective cohort of cancer patients admitted to three ICUs with the diagnosis of HCAP. CRP was sampled every other day from D0 do D6 of antibiotic prescription. Patients were classified according to an individual pattern of CRP-ratio response with the following criteria: fast response when CRP at day 4 of therapy was < 0.4 of day 0 CRP; slow response characterized by a continuous but slow decreased of CRP; non-response when CRP remained always above 0.8 of day 0 CRP; biphasic response characterized by an initial CRP decrease to levels < 0.8 of the day 0 CRP followed by a secondary rise > 0.8.
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